Potential of The Tyrosinase Enzyme Inhibition by Standardized Ethanol Extract And Ethyl Acetate Fraction of Bengkoang Peel (Pachyrhizus erosus L.)

This study examined the tyrosinase inhibitory potential of bengkoang peel standardised ethanolic extract and ethyl acetate fractions. 450 g powder (Pachyrhizus erosus L.) was macerated with 96% ethanol for 2 x 24 h, filtered, concentrated till viscous. Extract standardisation uses specific non-specific parameters. Microplate colorimetric inhibition assays were performed. The result plant determination identified as Pachyrhizus (L.) Urb. organoleptic test revealed a brownish-yellow viscous extract, fresh smell, bitter taste. Ethanol-soluble 47.60% water-soluble 22.42%. Bengkoang includes alkaloids, flavonoids, saponins, tannins, steroids. parameters showed loss drying (9.71%), water content (7.28%), total ash (9.91%), acid-insoluble (3.68%), no residual solvent content, lead (-0.2324±0.1729), cadmium (-0.0841±0.3418), TPC 1 101 CFU/g, TYMC 2.26 102 CFU/g. (103.9263) fraction (81.8606) IC50 values decrease enzyme activity compared to control (25.1235 ppm). These results show that met both particular quality standards. inhibited tyrosinase.